Prescription Required

Buxstat 40mg Tablet

by East West Pharma
Febuxostat (40mg)

₹77₹70

9% off
Buxstat 40mg Tablet

Introduction to Buxstat 40mg Tablet

This medication used in the treatment of hyperuricemia (elevated levels of uric acid in the blood), particularly in patients with gout. Gout is a type of arthritis caused by the buildup of uric acid crystals in the joints, leading to pain and inflammation.

 

Safety Advice for Buxstat 40mg Tablet

  • Moderate risk
  • High risk
  • Safe
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Moderate; limit alcohol intake; alcohol may exacerbate certain side effects of medicine.

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Limited data; consult healthcare provider for personalized advice; potential risks to the fetus.

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Limited data; consult healthcare provider for personalized advice; potential risks to the infant.

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Caution advised; potential risk of renal-related issues; monitor kidney function regularly.

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Generally safe; monitor liver enzymes during treatment for any abnormalities.

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It does not affect the driving ability.

How Buxstat 40mg Tablet works

Buxstat 40mg Tablet is a non-purine selective inhibitor, disrupts the activity of xanthine oxidase, a key enzyme in purine breakdown. By forming a stable complex with both forms of the enzyme, febuxostat effectively hinders its function. This inhibition reduces the production of uric acid from hypoxanthine, leading to lower levels of uric acid in the bloodstream. The therapeutic impact of febuxostat lies in its ability to decrease serum uric acid levels in individuals with hyperuricemia, a condition where uric acid concentration exceeds its solubility threshold. Notably, febuxostat's chemical structure differs from purines and pyrimidines, and it appears to specifically target xanthine oxidase without affecting other nucleotide-catabolic enzymes.

How To Use Buxstat 40mg Tablet

  • Do not chew it.
  • Take proper dose as per doctor’s recommendations.
  • Finish the full course for proper effect.

Special Precautions About Buxstat 40mg Tablet

  • It's important to discuss this with your healthcare provider, who may prescribe additional medications to prevent or manage these flares during the early stages of treatment.
  • Febuxostat is metabolized by the liver Patients with liver impairment may require dosage adjustments or closer monitoring.

Benefits Of Buxstat 40mg Tablet

  • Xanthine oxidase inhibitor for gout management.
  • Reduces uric acid levels.
  • Prevents gout attacks.
  • May improve joint symptoms associated with gout.

Side Effects Of Buxstat 40mg Tablet

  • Diarrhea
  • Headache
  • Increased liver enzymes
  • Nausea
  • Skin rash

Similar Medicine Of Buxstat 40mg Tablet

What If I Missed A Dose Of Buxstat 40mg Tablet

  • If you miss a dose, take it when you remember. 
  • If your next dose is close, skip the missed one and stay on your regular schedule. 
  • Avoid taking two doses at once. 
  • Consult your doctor for guidance on managing missed doses effectively.

Health And Lifestyle

You should take physical exercise for minimum 30 minutes. You should also focus on taking healthy diet for better health.

Disease Explanation

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Gout is a type of arthritis that causes pain and swelling in the joints due to the buildup of uric acid crystals. Uric acid is a waste product that normally dissolves in the blood and passes through the kidneys.

FAQ's on Buxstat 40mg Tablet

Can Buxstat cause kidney damage?

Buxstat may affect kidneys in different ways, though it is quite uncommon. You may experience blood in the urine, frequent urination, kidney stones, abnormal urine tests (increased level of proteins in the urine) and a reduction in the ability of the kidneys to function properly. Rarely, it may cause changes or decrease in urine amount due to inflammation in the kidneys (tubulointerstitial nephritis). Consult your doctor if your kidney functions get further affected.

What is Buxstat used for?

Buxstat is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain and heat in one or more joints.

What is the best time to take Buxstat?

Buxstat is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Buxstat in the body. You can take this medicine with or without food.

How long should I take Buxstat?

The dose and duration of Buxstat varies from person to person and will be decided by your doctor. It may take several months before Buxstat begins to prevent gout attacks. Do not stop taking Buxstat without the advice of your doctor even if you feel better.

Can Buxstat cause any liver problems?

Yes, Buxstat use may cause liver problems. Your doctor may advise you to get regular blood tests done before and during treatment with Buxstat to check how well your liver was working before and while taking this medicine. Inform your doctor if you notice symptoms such as fatigue, pain or tenderness on the right side of the abdomen or loss of appetite for several days or longer. It may also cause changes in the color of urine (dark or tea colored) and may make your skin or the white part of your eyes turn yellow (jaundice).

What are the things which I need to know while taking Buxstat?

You should be aware that Buxstat may cause serious heart problems which can be life-threatening in some cases. The symptoms of heart problems include chest pain, shortness of breath or trouble breathing, dizziness, fainting or feeling light-headed, rapid or irregular heartbeat. It may also cause numbness or weakness in one side of your body, slurring of speech and sudden blurry vision, or sudden severe headache. Immediately inform your doctor and seek medical help if you experience any of these symptoms.

What are the side effects of Buxstat?

Buxstat may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Buxstat include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.

Can I stop taking Buxstat on my own if I am fine and have no pain or swelling in joints?

No, do not stop taking Buxstat without the advice of your doctor even if you feel better. Discontinuation of medicine may increase the levels of uric acid. It may also worsen your symptoms due to the formation of new crystals of urate in and around your joints and kidneys.

check.svg Written By

Nish Kumar

B.Pharma + MBA

Content Updated on

Wednesday, 14 August, 2024

Prescription Required

Buxstat 40mg Tablet

by East West Pharma
Febuxostat (40mg)

₹77₹70

9% off
Buxstat 40mg Tablet

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