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Create ABHAIntroduction to Febustat 40 Tablet 15s
This medication used in the treatment of hyperuricemia (elevated levels of uric acid in the blood), particularly in patients with gout. Gout is a type of arthritis caused by the buildup of uric acid crystals in the joints, leading to pain and inflammation.
How Febustat 40 Tablet 15s works
Febustat 40 Tablet 15s is a non-purine selective inhibitor, disrupts the activity of xanthine oxidase, a key enzyme in purine breakdown. By forming a stable complex with both forms of the enzyme, febuxostat effectively hinders its function. This inhibition reduces the production of uric acid from hypoxanthine, leading to lower levels of uric acid in the bloodstream. The therapeutic impact of febuxostat lies in its ability to decrease serum uric acid levels in individuals with hyperuricemia, a condition where uric acid concentration exceeds its solubility threshold. Notably, febuxostat's chemical structure differs from purines and pyrimidines, and it appears to specifically target xanthine oxidase without affecting other nucleotide-catabolic enzymes.
How To Use Febustat 40 Tablet 15s
- Do not chew it.
- Take proper dose as per doctor’s recommendations.
- Finish the full course for proper effect.
Special Precautions About Febustat 40 Tablet 15s
- It's important to discuss this with your healthcare provider, who may prescribe additional medications to prevent or manage these flares during the early stages of treatment.
- Febuxostat is metabolized by the liver Patients with liver impairment may require dosage adjustments or closer monitoring.
Benefits Of Febustat 40 Tablet 15s
- Xanthine oxidase inhibitor for gout management.
- Reduces uric acid levels.
- Prevents gout attacks.
- May improve joint symptoms associated with gout.
Side Effects Of Febustat 40 Tablet 15s
- Diarrhea
- Headache
- Increased liver enzymes
- Nausea
- Skin rash
What If I Missed A Dose Of Febustat 40 Tablet 15s
- If you miss a dose, take it when you remember.
- If your next dose is close, skip the missed one and stay on your regular schedule.
- Avoid taking two doses at once.
- Consult your doctor for guidance on managing missed doses effectively.
Health And Lifestyle
You should take physical exercise for minimum 30 minutes. You should also focus on taking healthy diet for better health.
Disease Explanation
Gout is a type of arthritis that causes pain and swelling in the joints due to the buildup of uric acid crystals. Uric acid is a waste product that normally dissolves in the blood and passes through the kidneys.
Safety Advice for Febustat 40 Tablet 15s
- Moderate risk
- High risk
- Safe
Moderate; limit alcohol intake; alcohol may exacerbate certain side effects of medicine.
Limited data; consult healthcare provider for personalized advice; potential risks to the fetus.
Limited data; consult healthcare provider for personalized advice; potential risks to the infant.
Caution advised; potential risk of renal-related issues; monitor kidney function regularly.
Generally safe; monitor liver enzymes during treatment for any abnormalities.
It does not affect the driving ability.
FAQ's on Febustat 40 Tablet 15s
What is the best time to take febuxostat?
It is best taken in the morning. You can take febuxostat with or without food. Keep taking febuxostat every day, to prevent gout attacks. It may take a few weeks before you notice the full benefits of febuxostat.
What are the side effects of Febustat?
Febustat may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Febustat include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.
What is Febustat used for?
Febustat is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain and heat in one or more joints.
How long should I take Febustat?
The dose and duration of Febustat varies from person to person and will be decided by your doctor. It may take several months before Febustat begins to prevent gout attacks. Do not stop taking Febustat without the advice of your doctor even if you feel better.
What is febuxostat 40 mg used for?
Febuxostat oral tablet is used to treat hyperuricemia (constantly high levels of uric acid) in adults who have gout. It helps decrease your symptoms of gout. Symptoms of gout include pain, swelling, redness, heat, soreness, and stiffness in certain joints.
What is the best time to take Febustat?
Febustat is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Febustat in the body. You can take this medicine with or without food.
Can I stop taking Febustat on my own if I am fine and have no pain or swelling in joints?
No, do not stop taking Febustat without the advice of your doctor even if you feel better. Discontinuation of medicine may increase the levels of uric acid. It may also worsen your symptoms due to the formation of new crystals of urate in and around your joints and kidneys.
Is febuxostat safe for liver?
No instances of acute liver failure or chronic liver injury have been reported due to febuxostat, but the clinical experience with this agent is limited.
Can Febustat cause any liver problems?
Yes, Febustat use may cause liver problems. Your doctor may advise you to get regular blood tests done before and during treatment with Febustat to check how well your liver was working before and while taking this medicine. Inform your doctor if you notice symptoms such as fatigue, pain or tenderness on the right side of the abdomen or loss of appetite for several days or longer. It may also cause changes in the color of urine (dark or tea colored) and may make your skin or the white part of your eyes turn yellow (jaundice).
Does febuxostat increase creatinine?
However, after sub-group analysis of studies with treatment duration greater or equal to 6 months, a significantly lower serum creatinine in the patients with febuxostat treatment compared with those in the control group were observed.
What are the things which I need to know while taking Febustat?
You should be aware that Febustat may cause serious heart problems which can be life-threatening in some cases. The symptoms of heart problems include chest pain, shortness of breath or trouble breathing, dizziness, fainting or feeling light-headed, rapid or irregular heartbeat. It may also cause numbness or weakness in one side of your body, slurring of speech and sudden blurry vision, or sudden severe headache. Immediately inform your doctor and seek medical help if you experience any of these symptoms.
Is coffee good for uric acid?
Coffee is thought to reduce gout risk by lowering uric acid levels through several mechanisms . Coffee may lower uric acid levels by increasing the rate that your body excretes uric acid. Coffee is also thought to compete with the enzyme that breaks down purines in the body.
What is the side effect of uric acid?
These crystals can settle in the joints and cause gout, a form of arthritis that can be very painful. They can also settle in the kidneys and form kidney stones. If untreated, high uric acid levels may eventually lead to permanent bone, joint and tissue damage, kidney disease and heart disease.
Is gout curable or not?
The encouraging news is that almost all gout cases are treatable. In fact, gout is one of the few treatable and preventable forms of arthritis, an umbrella term for dozens of conditions that cause inflammation in the joints.
Can Febustat cause kidney damage?
Febustat may affect kidneys in different ways, though it is quite uncommon. You may experience blood in the urine, frequent urination, kidney stones, abnormal urine tests (increased level of proteins in the urine) and a reduction in the ability of the kidneys to function properly. Rarely, it may cause changes or decrease in urine amount due to inflammation in the kidneys (tubulointerstitial nephritis). Consult your doctor if your kidney functions get further affected.
Can I take febuxostat on an empty stomach?
Febuxostat is taken in tablet form once daily with or without food. The tablet should be swallowed with water. Your doctor will advise you about the correct dose.
How many days should I take febuxostat?
Remember, febuxostat should be taken every day to prevent a gout attack. It can take six months to become fully effective. It does not have any effect during a gout attack, although you should continue to take it regularly every day even if this happens.
Written By
Nish Kumar
B.Pharma + MBA
Content Updated on
Wednesday, 14 August, 2024
