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Introduction to DOLONEX 40 MG INJECTION
Dolonex 40mg Injection is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and swelling in various conditions such as osteoarthritis, rheumatoid arthritis, and musculoskeletal disorders. The active ingredient, Piroxicam (40mg), works by inhibiting the production of prostaglandins chemicals that contribute to pain and inflammation in the body. Dolonex 40mg Injection is typically administered when oral medications are not effective or suitable for a patient, offering fast relief for acute pain.
Safety Advice for DOLONEX 40 MG INJECTION
- High risk
- Moderate risk
- Safe
Alcohol consumption should be avoided while using Dolonex 40mg Injection. Drinking alcohol can increase the risk of gastrointestinal side effects, such as ulcers and bleeding.
Dolonex 40mg Injection is generally not recommended during pregnancy, especially during the third trimester. It may harm the developing fetus. Always consult a doctor before using this medication if pregnant or planning to conceive.
Piroxicam can pass into breast milk, so Dolonex 40mg Injection should be used with caution while breastfeeding. Your doctor may advise an alternative treatment if necessary.
Dolonex 40mg Injection may cause dizziness or drowsiness. If you experience these side effects, avoid driving or operating machinery until you feel fully alert.
People with pre-existing kidney issues should use Dolonex 40mg Injection cautiously, as NSAIDs can worsen kidney function. Your doctor may monitor your kidney function during treatment.
Liver disease patients should exercise caution when using Dolonex 40mg Injection, as it can affect liver function. Your doctor will assess the liver health before prescribing this medication.
How DOLONEX 40 MG INJECTION works
Dolonex 40mg Injection works by blocking the action of cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for producing prostaglandins. These chemicals promote inflammation, pain, and fever. By inhibiting these enzymes, Piroxicam reduces pain, swelling, and inflammation in the affected areas. This makes Dolonex 40mg Injection an effective treatment for managing acute pain and inflammation associated with various musculoskeletal and inflammatory conditions, such as arthritis and soft tissue injuries.
How To Use DOLONEX 40 MG INJECTION
- Dosage: The recommended dosage of Dolonex 40mg Injection is typically one injection per day depending on the severity of the condition. The exact dosage will be determined by your doctor based on your condition and response to treatment.
- Administration: Dolonex 40mg Injection is administered by a healthcare professional through intramuscular (IM) or intravenous (IV) injection. It is essential that this medication is only administered by a trained healthcare provider to minimize risks and ensure proper technique.
- Missed Dose: If you miss a dose, contact your healthcare provider to reschedule the injection. Do not attempt to administer an additional dose on your own.
Special Precautions About DOLONEX 40 MG INJECTION
- Gastrointestinal Issues: Dolonex 40mg Injection can increase the risk of gastrointestinal issues such as ulcers, bleeding, and perforation. People with a history of gastrointestinal disorders should inform their doctor before starting treatment.
- Cardiovascular Conditions: NSAIDs like Dolonex 40mg Injection can increase the risk of heart attack and stroke, especially when used in high doses or for prolonged periods. If you have a history of heart disease or stroke, consult your healthcare provider before using this medication.
- Allergies: If you are allergic to Piroxicam or any other NSAIDs, inform your healthcare provider. Symptoms of an allergic reaction include swelling, rash, and difficulty breathing.
Benefits Of DOLONEX 40 MG INJECTION
- Fast Pain Relief: Dolonex 40mg Injection provides fast relief from acute pain, especially in cases of rheumatoid arthritis, osteoarthritis, and other musculoskeletal conditions.
- Reduces Inflammation: It effectively reduces inflammation and swelling, helping to improve mobility and overall function in patients with inflammatory conditions.
- Short-Term Use: This medication is often used for short-term relief when oral NSAIDs are not effective or possible.
Side Effects Of DOLONEX 40 MG INJECTION
- Vomiting
- Stomach pain
- Nausea
- Indigestion
- Diarrhea
- Injection site reactions (pain, swelling, redness)
Similar Medicine Of DOLONEX 40 MG INJECTION
What If I Missed A Dose Of DOLONEX 40 MG INJECTION
- Take the missed dose as soon as you remember.
- If it's almost time for your next dose, skip the missed dose.
- Do not take two doses at the same time to compensate for the missed dose.
- Continue with your regular dosing schedule.
Health And Lifestyle
Avoid overuse of alcohol. Maintain Balance diet and stay hydrated. If you are regularly exercising than incorporate light exercise to manage pain and Inflammation better.
Drug Interaction
- Anticoagulants: Using Dolonex 40mg Injection alongside blood thinners such as warfarin can increase the risk of bleeding.
- Other NSAIDs: Avoid using Dolonex 40mg Injection with other NSAIDs to prevent an increased risk of gastrointestinal bleeding and ulcers.
- Antihypertensives: If you are taking medications for high blood pressure, Dolonex 40mg Injection may reduce the effectiveness of these drugs.
Drug Food Interaction
- Caffeine: Excessive caffeine intake can exacerbate the side effects of NSAIDs like Dolonex 40mg Injection, such as stomach irritation.
- Alcohol: Avoid alcohol while using Dolonex 40mg Injection as it can increase the risk of stomach bleeding and other gastrointestinal issues.
Disease Explanation
Pain- Pain signals the nervous system that something may be wrong, and can be sharp or dull, coming or going. It can be experienced in one area or all over. There are two types of pain: acute and chronic. Acute pain, sudden and often treated, can go away, while chronic pain can last for years and cause severe problems.
Tips of DOLONEX 40 MG INJECTION
Follow Dosage Instructions: Always follow your doctor’s instructions for dosage and administration to avoid complications.,Regular Monitoring: If you're on long-term treatment, regular check-ups, including kidney function and liver function tests, may be necessary.,Avoid Overuse: Limit the use of Dolonex 40mg Injection to the prescribed duration to reduce the risk of side effects.
FactBox of DOLONEX 40 MG INJECTION
- Composition:
- Piroxicam: 40mg
- Form: Injection (Intramuscular or Intravenous)
- Quantity: Typically 1 vial per dose
- Used For: Acute pain, inflammation, and swelling associated with musculoskeletal and inflammatory conditions
- Storage: Store at room temperature in a cool, dry place, away from direct sunlight. Keep out of reach of children.
Storage of DOLONEX 40 MG INJECTION
Store Dolonex 40mg Injection at room temperature, away from heat, light, and moisture. Ensure the product is kept out of reach of children.
Dosage of DOLONEX 40 MG INJECTION
Dolonex 40mg Injection is administered by a healthcare provider.,The usual dosage is one injection per day.
Synopsis of DOLONEX 40 MG INJECTION
Dolonex 40mg Injection is an effective treatment for managing acute pain and inflammation associated with musculoskeletal conditions, arthritis, and other inflammatory diseases. By inhibiting the production of prostaglandins, it provides relief from pain and reduces inflammation. Always follow your healthcare provider's instructions for use, and take appropriate precautions for safe and effective treatment.
FAQ's on DOLONEX 40 MG INJECTION
Can Dolonex be used with diuretics?
No. Dolonex should not be used with diuretics. Dolonex reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can I use Dolonex if I have peptic ulcer disease?
No. Dolonex is contraindicated in cases of active peptic ulcer disease. Dolonex is known to cause gastric ulceration and bleeding.
What is the difference between Dolonex and diclofenac?
Both Dolonex and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Dolonex.
How long does Dolonex work?
Dolonex is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Is Dolonex a blood thinner?
No. Dolonex is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Can Dolonex be used in the treatment of allergy?
No. Dolonex is not a drug to treat allergy. It is a pain killer.
Is Dolonex affective in gout management?
Yes. Dolonex can be given for the treatment of acute gout. Research studies have shown Dolonex to be highly effective in the treatment of acute gout.
Is Dolonex a sulfa drug?
Dolonex is a sulphur containing compound. Dolonex can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Can I use Dolonex if I am pregnant?
No. Dolonex should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
What is the difference between Dolonex and nimesulide?
Both Dolonex and nimesulide are pain killers. However, Dolonex is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Can you donate blood when on the medication with Dolonex?
Yes. You can donate blood when on Dolonex. Do inform your doctor before donating blood.
What is the difference between Dolonex and naproxen?
Both Dolonex and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Dolonex.
What is the difference between Dolonex and tramadol?
Dolonex is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Can Dolonex be used along with Losartan?
No. Dolonex should not be combined with Losartan. It is important to note that Dolonex decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dolonex.
Is Dolonex a muscle relaxant?
No. Dolonex is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Can I use Dolonex if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Can Dolonex be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Dolonex or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Dolonex.
Can you get high by using Dolonex?
No. Dolonex is not known to cause high. It is a non-narcotic painkiller.
What are the contraindications for Dolonex?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
What are the serious side effects of Dolonex?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Written By
Harsh Thakur
Content Updated on
Sunday, 16 Feburary, 2025Prescription Required
DOLONEX 40 MG INJECTION
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