Combigan Ophthalmic Solution 5ml

Combigan combines two active ingredients: brimonidine tartrate (0.2%) and timolol maleate (0.5%). Brimonidine Tartrate: An alpha-2 adrenergic receptor agonist that decreases aqueous humor production and enhances uveoscleral outflow, leading to reduced eye pressure. Timolol Maleate: A non-selective beta-adrenergic receptor blocker that lowers IOP by reducing the production of aqueous humor. The synergistic action of these components provides a more significant IOP reduction than either agent alone.

• Wash your hands thoroughly.
• Tilt your head back and look upward.
• Gently pull down the lower eyelid to create a small pocket.
• Hold the dropper above the eye and squeeze out one drop into the pocket.
• Close your eye and apply gentle pressure to the inner corner for about 1 minute to prevent drainage.
• Avoid touching the dropper tip to any surface, including the eye, to maintain sterility.

• Medical History: Inform your doctor if you have conditions such as asthma, chronic obstructive pulmonary disease (COPD), heart diseases, diabetes, thyroid disorders, or depression.
• Allergic Reactions: Discontinue use and seek medical attention if you experience symptoms like eye redness, swelling, or itching.
• Operating Machinery: Combigan may cause temporary blurred vision or drowsiness. Avoid driving or operating heavy machinery until you are sure you can perform such activities safely.
• Surgical Procedures: Notify your surgeon or anesthetist that you are using Combigan if you are scheduled for surgery.

• Effective IOP Reduction: Combigan Ophthalmic Solution combines two mechanisms to lower eye pressure more effectively than monotherapy.
• Convenient Dosing: Twice-daily administration simplifies treatment regimens.
• Proven Safety Profile: Clinical trials have demonstrated the efficacy and safety of Combigan in managing glaucoma and ocular hypertension.

• Common side effects may include: Eye irritation or redness, Burning or stinging sensation, Dry mouth, Headache, Drowsiness or fatigue.
• If side effects persist or worsen, consult your healthcare provider.

• Consistent Use: Apply Combigan at the same times each day to maintain stable eye pressure.
• Monitor Vision: Regularly check your vision and report any changes to your eye care specialist.
• Scheduled Appointments: Keep regular appointments with your ophthalmologist to monitor eye health and treatment efficacy.

• Adults & Elderly: One drop of Combigan Ophthalmic Solution in the affected eye(s) twice daily, 12 hours apart.
• Children: Not recommended for use in children under 2 years of age. Consult a doctor for pediatric usage.
• Overdose: If an excessive amount is applied, rinse the eye with water and seek medical advice if necessary.