Prescription Required

Zyrifa Capsule

by Zydus Cadila

₹45

Zyrifa Capsule

Introduction to Zyrifa Capsule

Zyrifa Capsule is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Safety Advice for Zyrifa Capsule

  • High risk
  • Moderate risk
  • Safe
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Consuming alcohol while taking Zyrifa Capsule may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

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Zyrifa Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Zyrifa Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

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Zyrifa Capsule may cause side effects which could affect your ability to drive.<BR>Zyrifa Capsule occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.

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Zyrifa Capsule should be used with caution in patients with kidney disease. Dose adjustment of Zyrifa Capsule may be needed. Please consult your doctor.<BR>Kidney function tests are advisable before the start of this medicine.

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Zyrifa Capsule should be used with caution in patients with liver disease. Dose adjustment of Zyrifa Capsule may be needed. Please consult your doctor.<BR>Regular monitoring of liver function tests is advised before and after the start of the treatment.

How Zyrifa Capsule works

Zyrifa Capsule is a combination of four medicines: Isoniazid, rifampicin, ethambutol and pyrazinamide which treat tuberculosis. Isoniazid works by preventing the TB bacteria from forming their own protective covering, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide on the other hand, work by slowing the growth of these bacteria.

How To Use Zyrifa Capsule

  • Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Zyrifa Capsule is to be taken empty stomach. Avoid Zyrifa Capsule with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Side Effects Of Zyrifa Capsule

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Watery eyes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Visual impairment

FAQ's on Zyrifa Capsule

Can the use of Zyrifa cause discoloration of the urine?

Yes, Zyrifa contains Rifampicin. It can cause temporary discoloration of your teeth, sweat, urine, saliva and tears (red, orange or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Contact your doctor if you notice discoloration of urine accompanied with stomach pain, loss of appetite and jaundice (yellowing of your skin or eyes).

How to take Zyrifa?

Take Zyrifa on an empty stomach which means at least one hour before and two hours after a meal and with full glass of water.

Can I discontinue Zyrifa if I feel well?

No, do not discontinue Zyrifa. Take the proper course of a drug that has been prescribed for you even if you begin to feel better. If you stop taking Zyrifa then your infection may become worse, difficult to treat and it may result in drug-resistant TB (drugs you are taking may no longer work).

Can I take oral contraceptive pills while taking Zyrifa?

No, Zyrifa can make birth control pills less effective. So, ask your doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Can Zyrifa cause visual impairment?

Zyrifa contains Ethambutol which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.

Can I drink alcohol while taking Zyrifa?

No, avoid drinking alcohol while taking Zyrifa. Drinking alcohol will increase the risk of hepatitis caused by Zyrifa because of isoniazid.

What are the instructions for storage and disposal of Zyrifa?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Prescription Required

Zyrifa Capsule

by Zydus Cadila

₹45

Zyrifa Capsule

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