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Prescription Required

Pyzina 1000 Tablet

by Lupin Ltd
Pyrazinamide (1000mg)

₹110₹99

10% off
Pyzina 1000 Tablet

Introduction to Pyzina 1000 Tablet

Pyzina 1000 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification.

Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Safety Advice for Pyzina 1000 Tablet

  • Moderate risk
  • High risk
  • Safe
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Caution is advised when consuming alcohol with Pyzina 1000 Tablet. Please consult your doctor.

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Pyzina 1000 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Pyzina 1000 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

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It is not known whether Pyzina 1000 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

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Pyzina 1000 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Pyzina 1000 Tablet may be needed. Please consult your doctor.<BR>Kidney function tests are advised before you start taking this medicine.

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Pyzina 1000 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pyzina 1000 Tablet may be needed. Please consult your doctor.<BR>Regular monitoring of liver function tests is advised before and after the start of the treatment.

How Pyzina 1000 Tablet works

Pyzina 1000 Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

How To Use Pyzina 1000 Tablet

  • Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyzina 1000 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Benefits Of Pyzina 1000 Tablet

  • Pyzina 1000 Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side Effects Of Pyzina 1000 Tablet

  • Jaundice
  • Hepatitis (viral infection of liver)
  • Increased liver enzymes
  • Joint pain

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FAQ's on Pyzina 1000 Tablet

Is TB medicine taken empty stomach?

MUNICH — When first-line tuberculosis (TB) drugs are taken with food, there is a reduction in maximum plasma concentration and bioavailability of the drug than when taken on an empty stomach, according to the results of a new pharmacokinetic study.

Is Pyzina bactericidal?

Pyzina is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

How does Pyzina work/treat tuberculosis?

Pyzina kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Pyzina is not known

How does pyrazinamide treat tuberculosis?

How it works: Pyrazinamide is a chemically synthesised bacteriocidal antibiotic. It converts a special enzyme to an active form which inhibits the synthesis of fatty acids; this disrupts the cell membrane and disables energy production which is necessary for the survival of the TB bacteria.

What is the side effect of pyrazinamide?

Nausea, vomiting, loss of appetite, or mild muscle/joint pain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Does pyrazinamide cause hepatitis?

Many cases of pyrazinamide hepatotoxicity are severe and prolonged, and fatal instances have occurred. Pyrazinamide has not been linked to chronic hepatitis or vanishing bile duct syndrome. There is no cross reactivity of the hepatic injury with other currently available antituberculosis agents.

When should I take pyrazinamide?

It usually is taken once a day (at the same time each day) or in larger doses twice a week. Pyrazinamide may be taken with or without food. Follow the directions on your prescription label carefully, and ask your pharmacist or doctor to explain any part you do not understand. Take pyrazinamide exactly as directed.

How does Pyzina cause hyperuricemia and gout?

Following oral intake of Pyzina, it gets converted in the body to pyrazinoic acid (active chemical form of Pyzina). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

What is pyrazinamide used for?

Pyrazinamide is used to treat tuberculosis (TB) in adults and children. Pyrazinamide must be used with other TB medicines. Tuberculosis can become resistant to treatment if pyrazinamide is used alone.

How long should I take pyrazinamide?

Your child should start to feel better and have fewer symptoms after taking the TB medicines for about 2 weeks. However, they must continue to take the medicine every day until the doctor says to stop treatment. This will be for 2 months for pyrazinamide and at least 6 months for the other medicines.

Why is pyrazinamide and isoniazid used together?

Rifampin, isoniazid, and pyrazinamide combination is used to treat tuberculosis (TB) infection. It may be taken alone or with one or more other medicines for TB. Rifampin belongs to the class of medicines called antibiotics and works to kill or prevent the growth of bacteria.

Which fruit is good for TB patient?

Fruits and vegetables like orange, mango, sweet pumpkin and carrots, guava, amla, tomato, nuts and seeds are an excellent source of Vitamin A, C and E. These foods must be included in the daily diet regime of a TB patient. TB patients tend to experience loss in appetite.

How do you know if TB treatment is working?

Physical Signs That TB Treatment Is Working Overall improvement in the way one feels. Weight gain. Increased appetite. Improvement in strength and stamina.

What is Pyzina and what is it used for?

Pyzina is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

When is the best time to take TB medication?

The medications work best if they are taken all together one hour before, or two hours after, food and preferably with water. Ideally, the medications should be taken at the same time each day. For patients who have nausea, the medications can be taken with light food (eg, dry toast).

check.svg Written By

Ashwani Singh

Content Updated on

Saturday, 2 March, 2024

Prescription Required

Pyzina 1000 Tablet

by Lupin Ltd
Pyrazinamide (1000mg)

₹110₹99

10% off
Pyzina 1000 Tablet

Pyzina 1000 Tablet

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