Mefril D 80mg/250mg Tablet is a dual-component medicine, comprising Drotaverine and Mefenamic Acid, which fundamentally aids in dealing with a range of conditions encompassed by muscular spasms and ache. It is specifically prescribed for the subsequent health concerns.

This medication is particularly beneficial in easing spasmodic stomach aches, providing solace to those suffering from discomfort in the abdominal area.

For those grappling with the hardships of irritable bowel syndrome, this medication provides reprieve from spasms occurring in the gastrointestinal tract.

It zeroes in on the smooth muscle spasms in the uterus, providing a respite from the discomfort brought about by menstruation.

During childbirth, cervical spasms may arise, amplifying the agony experienced by the mother. This medication is recommended to mitigate these spasms, facilitating a more tolerable labor experience.

The medicine is also advised to alleviate the chest pain resulting from muscle spasms. By focusing on the smooth muscles in the chest region, it plays a role in eliminating the discomfort.

In relation to gallstones, causing grave pain due to spasms in the gallbladder or bile ducts, this dual-component medicine is deployed to pacify the spasms and relative pain.

For persons plagued with renal colic, hallmarked by spasms and pain in the kidneys, this medication proves to be effective in bestowing relief and enhancing overall comfort.

Drotaverine unfolds its therapeutic influence through antispasmodic and vasodilatory actions. It suppresses the phosphodiesterase enzyme IV, lowering cyclic AMP levels and calcium ions, leading to the expansion of unstipped muscles and blood vessels, thereby mitigating smooth muscle spasms. Mefenamic Acid, in contrast, brings into play its role by curbing the synthesis and release of prostaglandins, effectively reducing inflammation and pain.

Adhere to the prescribed quantity and advice given by your healthcare specialist for optimum outcome.

Potential side impacts encompass hypotension, headache, tachycardia, nausea, vertigo (for Drotaverine), and nausea, vomiting, abdominal discomfort, and headache (for Mefenamic Acid). Should any side effects persist or aggravate, reach out to your healthcare practitioner.

Drotaverine is contraindicated in severe renal, hepatic, and cardiac dysfunction. Mefenamic Acid is contraindicated in inflammatory bowel disease and peptic ulcer.

If a dose is forgotten, consume it as soon as you recall. However, if the next scheduled dose is near, bypass the forgotten one and proceed with your normal dosing regimen. Evade doubling the dose to compensate for a missed one.