Letrogest is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

Yes, you can take irbesartan and Letrogest together. However, be careful and keep a regular check on your blood pressure since Letrogest may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Letrogest is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent the cancer from growing.

If the breast tumor is in advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letrogest till the tumor shows progression. In cases where Letrogest is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until tumor comes back, whichever is first. It can also be given as a sequential treatment 2 years of Letrogest followed by 3 years of tamoxifen.

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letrogest include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.

Although it is very uncommon but Letrogest may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

This could be a sign of hot flushes which is a very common side effect of Letrogest. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letrogest. However, in some people the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.