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Introduction to Insulatard NOVOLET 100IU Suspension for Injection
- It contains Insulin Isophane, also known as NPH (Neutral Protamine Hagedorn) insulin.
- It is an intermediate-acting insulin used to control blood sugar levels in people with diabetes mellitus.
- It is designed to manage blood glucose levels over a longer period, providing basal insulin coverage throughout the day and night.
Safety Advice for Insulatard NOVOLET 100IU Suspension for Injection
- Moderate risk
- High risk
- Safe
Limit alcohol consumption as it can increase the risk of hypoglycemia.
Insulin is generally safe during pregnancy, but dose adjustments may be necessary.
Insulin is safe during breastfeeding, but consult your doctor for appropriate dosage.
Be cautious when driving, as hypoglycemia can impair your ability to perform these tasks safely.
Use with caution if you have kidney disease. Regular kidney function tests and dose adjustments may be required.
Use with caution if you have liver disease. Regular liver function tests and dose adjustments may be required.
How Insulatard NOVOLET 100IU Suspension for Injection works
Insulin Isophane (NPH): It is an intermediate-acting insulin that helps to lower blood glucose levels by facilitating the uptake of glucose into cells and inhibiting glucose production by the liver.
How To Use Insulatard NOVOLET 100IU Suspension for Injection
- Dosage: Follow the dosage and administration schedule prescribed by your healthcare provider, which will be tailored to your individual needs based on your blood sugar levels.
- Administration: The injection is typically administered subcutaneously (under the skin) in areas such as the abdomen, thigh, or upper arm.
- Rotate the injection sites to prevent lipodystrophy (changes in fat tissue under the skin).
- The injection should be given about 30 minutes before a meal, depending on your doctor's instructions.
Special Precautions About Insulatard NOVOLET 100IU Suspension for Injection
- Inform your doctor if you have any known allergies to insulin or any other medications.
- Discuss with your doctor if you have any underlying health conditions, particularly liver or kidney disease, or if you have frequent episodes of hypoglycemia.
Benefits Of Insulatard NOVOLET 100IU Suspension for Injection
- Provides steady and prolonged blood sugar control, mimicking the body's natural insulin release.
- Reduces the risk of hyperglycemia (high blood sugar) throughout the day and night.
- Can be used alone or in combination with other types of insulin or oral antidiabetic medications.
Side Effects Of Insulatard NOVOLET 100IU Suspension for Injection
- Hypoglycemia (low blood glucose level)
- Injection site allergic reaction
- Lipodystrophy (skin thickening or pits at the injection site)
- Weight gain
- Edema (swelling)
Similar Medicine Of Insulatard NOVOLET 100IU Suspension for Injection
What If I Missed A Dose Of Insulatard NOVOLET 100IU Suspension for Injection
- If you miss a dose, take it as soon as you remember, ensuring that it is close to your next meal.
- If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
- Do not double the dose to catch up.
Health And Lifestyle
Follow a balanced diet tailored to your diabetic condition, focusing on low-glycemic index foods, whole grains, lean proteins, and plenty of vegetables. Engage in regular physical activity to help manage blood sugar levels and improve overall health. Monitor your blood sugar levels regularly as advised by your healthcare provider, and keep a record of your readings. Avoid smoking and limit alcohol intake to reduce the risk of complications associated with diabetes. Stay educated about diabetes management and always carry medical identification indicating that you have diabetes.
Drug Interaction
- Oral Antidiabetic Drugs
- Beta-blockers
- Corticosteroids
- Diuretics
Drug Food Interaction
- Alcohol
Disease Explanation
Type 1 diabetes is an autoimmune condition where the body attacks the insulin-producing beta cells in the pancreas, leading to a complete lack of insulin production. Type 2 diabetes is characterized by insulin resistance, where the body’s cells do not respond effectively to insulin, and often a relative insulin deficiency.
FAQ's on Insulatard NOVOLET 100IU Suspension for Injection
Can Insulatard cause hypoglycemia? How do I prevent it?
Yes. The most common side effect of Insulatard is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, don’t skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you. Take all your medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.
How does biphasic isophane insulin work?
Insulin isophane is a recombinant human insulin analogue (genetically modified insulin that is grown in a laboratory and similar to human insulin). It is an intermediate acting insulin preparation. Insulin isophane acts by replacing the normal production of insulin and by helping transfer sugar from the blood into other body tissues where it is utilized to generate energy. It also stops the liver from producing more sugar. Intermediate acting insulin preparations start acting within an hour or 2 of injection, and reach a period of peak activity that lasts up to 7 hours, following which the action trails off overall duration of action ranges from 18 to 24 hours.
Is Insulatard given as an injection into a vein (intravenous)?
Yes, sometimes, in specific situations like diabetic ketoacidosis, severe hyperglycemia etc, Insulatard may be given as an injection into a vein (intravenous). However, it is only given by a doctor, under continuous monitoring of blood sugar levels in a hospital setting.
What is Insulatard? How is it made?
Insulatard is a man-made version of human insulin, produced by the process of biotechnology called recombinant DNA technology. It is sold as a sterile, aqueous, clear, and colorless solution that contains insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, sodium chloride etc.
What are the other side effects of Insulatard? How to prevent them?
The other side effects of Insulatard are injection site reactions such as redness, itching, pain and swelling. However, these are temporary and usually resolve on their own. Rarely, it can also cause lipodystrophy, which means abnormal changes in the fat tissues due to repeated insulin injections in the same area of the skin. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.
How should Insulatard be used?
Insulatard is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs, or upper arms. Never inject Humalog into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection, for one or two weeks.Then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.
Is Insulatard safe to use in pregnancy?
Yes. Insulatard is safe to use in pregnancy if prescribed by a doctor. However, please inform your doctor if you are pregnant, planning to conceive or breastfeeding before using Insulatard. You may require dose modifications and your doctor will advise you to monitor your blood sugar levels regularly. You must follow the instructions of your doctor to get maximum benefit.
When does the dosage of Insulatard need to be changed?
You should consult your doctor for dose adjustment if you experience weight gain or loss, increased stress, illness, changes in diet such as missed meals or if you are taking alcohol. Your dose may also change if you have recently changed your exercise regime or are taking any medicines. Also, you must be vigilant on the changes you experience while first using Insulatard. For eg, you may notice certain side effects that are usually temporary but if these are very severe, you may need dose modifications.
Written By
Pranav ayush
MBA in Pharmaceutical
Content Updated on
Wednesday, 4 September, 2024Prescription Required
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