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Prescription Required

Glynase MF Tablet 10s

by USV Ltd
Glipizide (5mg) + Metformin (500mg)

₹20₹19

5% off
Glynase MF Tablet 10s

Introduction to Glynase MF Tablet 10s

Glynase MF Tablet 10s is a mix of Glipizide and metformin anti-diabetic drugs formulated to stabilize blood glucose levels in adults suffering from type 2 diabetes. It's worth noting that it is not recommended for type 1 diabetes.

This combination leverages the combined power of Glipizide and Metformin. Glipizide triggers insulin production by the pancreas, assisting glucose breakdown. On the other hand, Metformin enhances the body's sensitivity to insulin and curtails excessive glucose generation in the liver.

It is typically consumed during meals to bolster effectiveness. If a dose is overlooked, take it as soon as you recall. Nevertheless, if the upcoming scheduled dose is imminent, disregard the forgotten one. Prevent doubling up in an attempt to compensate for a forgotten dose.

Regular side effects encompass stomach discomfort, queasiness, diarrhoea, headache, or minor cold symptoms. However, if you experience serious hypoglycaemia (extreme fatigue, blurry vision, confusion, etc), indications of heart complications, or symptoms of lactic acidosis (uncommon muscle pain, difficulty breathing), seek urgent medical care.

Convey to your medical expert about any allergies to Glipizide, Metformin, or related compounds. Discuss your health history, particularly regarding kidney problems, heart diseases, or if you are over 80 years of age. In cases of vomiting, diarrhoea, or fever, connect with your doctor immediately to prevent dehydration.

If you miss a dose, take it immediately. However, if the next planned dose is near, it is recommended to skip the missed dosage. Avoid doubling up in an attempt to compensate for a missed dosage.

Safety Advice for Glynase MF Tablet 10s

  • Moderate risk
  • High risk
  • Safe
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It is dangerous to mix medicine with alcohol, as it may lead to negative side effects and heightened risks.

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It could be risky during pregnancy. Consultation with your doctor is necessary to assess the benefits and possible risks before taking it.

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Medication usage while breastfeeding is possibly unsafe, with limited evidence suggesting potential harm to the baby through breast milk.

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Medicine usage in kidney disease should be cautious, with dose adjustments and consistent monitoring of kidney function recommended, particularly in severe kidney disease.

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Proceed with caution in liver disease withmedicine. Starting doses should be low in mild to moderate liver disease, and its usage is discouraged in severe liver disease.

How Glynase MF Tablet 10s works

Analogous to the solitary Glipizide, yet amalgamated with Metformin, this synthesis offers twin frameworks for blood sugar regulation in type 2 diabetes. Glipizide triggers insulin discharge, while Metformin diminishes glucose formation.

How To Use Glynase MF Tablet 10s

  • Adhere to your physicians' instructions for this medication, consuming it in the stipulated quantity and period.
  • You can ingest this medication with or without a meal, however ensuring a uniform time each day is suggested for optimal outcomes.
  • Ingest the medication in its entirety; refrain from masticating, pulverizing, or fragmenting it.

Special Precautions About Glynase MF Tablet 10s

  • Glipizide enhances insulin release, which can lead to hypoglycaemia (low blood sugar). The risk of hypoglycaemia is higher with higher doses of glipizide. Patients should be educated about recognizing the signs and symptoms of hypoglycaemia, and blood glucose levels should be monitored regularly. Dosage adjustments or changes in diet may be necessary to manage hypoglycaemia.
  • Glipizide belongs to the sulfonylurea class, and individuals with a known sulpha allergy should use glipizide with caution. Cross reactivity with sulpha antibiotics is rare, but it's still important to be aware of the possibility.
  • Both glipizide and metformin can cause gastrointestinal side effects, including nausea and diarrhoea. These effects may be more pronounced when the two medications are used together. Inform healthcare providers about any persistent or severe gastrointestinal symptoms.

Benefits Of Glynase MF Tablet 10s

  • Manages blood sugar levels Enhances insulin sensitivity. Reduces glucose production Supports overall glycaemic control.

Side Effects Of Glynase MF Tablet 10s

  • Dizziness
  • Diarrhea
  • Nervousness
  • Tremors
  • Hypoglycemia (low blood glucose level)
  • Flatulence
  • Headache
  • Nausea
  • Vomiting
  • Weight gain
  • Abdominal discomfort
  • Abnormal sensation

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What If I Missed A Dose Of Glynase MF Tablet 10s

If you miss a dose, take it when you remember. If your next dose is close, skip the missed one and stay on your regular schedule. Avoid taking two doses at once. Consult your doctor for guidance on managing missed doses effectively.

Disease Explanation

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Type 2 diabetes mellitus is a chronic condition that affects how the body regulates and uses sugar (glucose) as a fuel. It occurs when the body becomes resistant to insulin, a hormone that helps glucose enter the cells, or when the pancreas cannot produce enough insulin. As a result, the blood sugar levels become too high and can cause damage to various organs and tissues.

FAQ's on Glynase MF Tablet 10s

What is Glynase-MF?

Glynase-MF is a combination of two medicines: Glipizide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glipizide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

What is another name for Gliclazide?

Gliclazide, sold under the brand name Diamicron among others, is a sulfonylurea type of anti-diabetic medication, used to treat diabetes mellitus type 2. It is used when dietary changes, exercise, and weight loss are not enough.

Is it safe to take alcohol while I am also taking Glynase-MF?

No, it is not safe to take Glynase-MF along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Can the use of Glynase-MF cause hypoglycemia?

Yes, the use of Glynase-MF can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you.

Are there any specific conditions in which Glynase-MF should not to be taken?

The use of Glynase-MF should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Does glipizide lower blood sugar immediately?

Glipizide helps with the release of insulin that occurs after a meal. These effects occur within 30 minutes of an oral dose of glipizide, even though it takes one to three hours for peak plasma concentrations to occur.

What glipizide metformin used for?

Glipizide and Metformin combination is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. Normally, after you eat, your pancreas releases insulin to help your body store excess sugar for later use.

What is better metformin or glipizide?

Another comparative trial found that metformin provided better blood sugar control than glipizide. Those taking metformin in the study had better fasting plasma glucose levels than glipizide after 24, 36, and 52 weeks. Those taking metformin also had a lower HbA1c level than those taking glipizide after 52 weeks.

What is type 1 and type 2 diabetes?

If you have either type 1 or type 2 diabetes, it means you have too much glucose (a type of sugar) in your blood. This is the same for both types. But the difference between them is how this happens. If you have type 1 diabetes, it means you have an autoimmune condition.

What is glynase used for?

Glyburide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.

Is Metformin better than glyburide?

CONCLUSIONS Glyburide and metformin are comparable oral treatments for GDM regarding glucose control and adverse effects. Their combination demonstrates a high efficacy rate with a significantly reduced need for insulin, with a possible advantage for metformin over glyburide as first-line therapy.

How much glipizide Can I take a day?

Adults—At first, 5 milligrams (mg) once a day taken at least 30 minutes before breakfast. Your doctor may adjust your dose if needed. The dose is usually not more than 40 mg per day.

What are the possible side effects of Glynase-MF?

The use of Glynase-MF is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.

What is the safest diabetic medication?

Metformin is still the safest and most effective type 2 diabetes medication, said Bolen. She is an assistant professor of medicine at Case Western Reserve Universitys Center for Health Care Research and Policy, in Cleveland.

What is the best time of day to take glipizide?

Take the glipizide regular tablet 30 minutes before your first meal of the day. Take the glipizide extended-release tablet with your first meal of the day.

Is it better to take Metformin before or after meals?

Metformin should be taken with meals to help reduce stomach or bowel side effects that may occur during the first few weeks of treatment. Swallow the tablet or extended-release tablet whole with a full glass of water. Do not crush, break, or chew it.

Can glipizide cause liver damage?

Serious side effects of Glucotrol include hypoglycemia, jaundice, liver damage, fever, bleeding or bruising, skin changes, SIADH, and porphyria.

What are the instructions for storage and disposal of Glynase-MF?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Glynase-MF cause lactic acidosis?

Yes, the use of Glynase-MF can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glynase-MF and immediately consult your doctor.

What is the best medicine for diabetes type 2?

Metformin is generally the preferred initial medication for treating type 2 diabetes, unless theres a specific reason not to use it. Metformin is effective, safe, and inexpensive. It may reduce the risk of cardiovascular events. Metformin also has beneficial effects when it comes to reducing A1C results.

Is glipizide bad for the kidneys?

Previous research indicates that the diabetes drugs sitagliptin and glipizide may not cause considerable kidney damage. New clinical trial results presented during the American Society of Nephrologys Annual Kidney Week compared the two drugs.

Can the use of Glynase-MF lead to Vitamin B12 deficiency?

Yes, the use of Glynase-MF can cause Vitamin B12 deficiency on long-term use. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in the hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

check.svg Written By

Shubhadip Sarkar

Content Updated on

Saturday, 27 January, 2024

Prescription Required

Glynase MF Tablet 10s

by USV Ltd
Glipizide (5mg) + Metformin (500mg)

₹20₹19

5% off
Glynase MF Tablet 10s

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