Avoid alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis.
Use with caution if you have liver disease.
Use with caution if you have kidney disease.
Consult your doctor before using this medication during pregnancy.
Consult your doctor before using this medication while breastfeeding.
Avoid driving if you experience dizziness.
Gliclazide: Stimulates the release of insulin from the pancreas, helping to lower blood sugar levels. Metformin: Decreases glucose production in the liver, reduces the absorption of glucose from the intestines, and improves insulin sensitivity, allowing the body to use insulin more effectively.
Type 2 diabetes is a chronic condition characterized by high blood sugar levels due to the body's inability to use insulin effectively.
Janumet (sitagliptin / metformin) is a combination medication containing sitagliptin and metformin. This medication is an add-on to diet and exercise to improve blood sugar control in people with type 2 diabetes.
In a double-blind, multicenter, multinational study, the long-term efficacy and safety of Diamicron(R)MR, a new gliclazide formulation taken once daily at lower dose (30-120 mg/day) was compared with Diamicron(R) (80-320 mg/day) taken twice daily in type 2 diabetic outpatients.
The use of Diamicron Mex should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.
Yes, the use of Diamicron Mex can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.
Erectile dysfunction — the inability to get or maintain an erection firm enough for sex — is common in men who have diabetes, especially those with type 2 diabetes. It can stem from damage to nerves and blood vessels caused by poor long-term blood sugar control.
Diamicron MR tablets are known as modified-release tablets. They are designed to release the gliclazide gradually, so that there is an effective level of gliclazide in the blood for 24 hours.
Yes, the use of Diamicron Mex can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.
DIAMICRON 60 mg MR is used to control blood glucose (sugar) in patients with Type II diabetes mellitus. This type of diabetes is also known as non-insulin-dependent diabetes (NIDDM), or maturity-onset diabetes).
The recommended daily dose is one to four tablets (maximum 120 mg) in a single intake at breakfast time. This depends on the response to treatment. Diamicron 30 mg is for oral use. Take your tablet(s) with a glass of water at breakfast time (and preferably at the same time each day).
Theres no cure for type 2 diabetes, but losing weight, eating well and exercising can help you manage the disease. If diet and exercise arent enough to manage your blood sugar, you may also need diabetes medications or insulin therapy.
For standard-release gliclazide, the maximum daily dose is 320mg (4 x 80mg tablets). If you need to take more than 160mg (2 x 80mg tablets) a day, take the tablets twice a day with your morning and evening meals. For slow-release gliclazide, the maximum daily dose is 120mg. Take your dose once a day before breakfast.
No, it is not safe to take alcohol along with Diamicron Mex. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.
Diamicron Mex is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.
The use of Diamicron Mex is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.
The maximum recommended daily dose is 120 mg. Switching from Diamicron 80 mg tablets to Diamicron 30 mg modified release tablets: 1 tablet of Diamicron 80 mg is comparable to 1 tablet of Diamicron 30 mg MR Tablets.
Yes, the use of Diamicron Mex can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Diamicron Mex and immediately consult your doctor.
Both medications help to reduce blood glucose but work differently. Metformin reduces the amount of glucose produced in the liver, and also makes muscle tissue absorb more glucose; gliclazide increases the amount of insulin produced by the pancreas.
Hypoglycaemia is the most common and serious side effect of Diamicron. It is due to an extension of the therapeutic effect. Other common adverse effects include: Weight gain.
MBA in Pharmaceutical
Content Updated on
Sunday, 14 July, 2024Prescription Required
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