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Introduction to Pirocol 20mg Injection
It is a pain-relieving medicine that helps in treating moderate to severe pain.
- This medicine relieves pain and swelling in conditions related to muscles and joints.
- It is generally injected when oral administration is not suitable.
Safety Advice for Pirocol 20mg Injection
- Moderate risk
- High risk
- Safe
Caution is advised when consuming alcohol with this drug. Please consult your doctor.
It is unsafe to use during pregnancy as it may pose risk to the developing baby. Please consult your doctor.
It is considered to be safe to use during breastfeeding. The drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
It may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
It should be used cautiously in patients with severe kidney disease. Dose adjustment of the drug may be needed. Please consult your doctor.
The drug should be used with caution in patients with liver disease. Dose adjustment of drug may be needed. Please consult your doctor.
How Pirocol 20mg Injection works
It is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
How To Use Pirocol 20mg Injection
- Your doctor or nurse will give you this medicine. Kindly do not self administer.
- You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
- Strictly follow the dose and duration suggested by a healthcare professional.
Special Precautions About Pirocol 20mg Injection
- If side effects persist or get worse, you should let your doctor know.
- Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
- Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
- Pregnant and breastfeeding mothers must consult with their doctors before using the medicine.
Benefits Of Pirocol 20mg Injection
- Helps to relieve pain in conditions like osteoarthritis and rheumatoid arthritis.
Side Effects Of Pirocol 20mg Injection
- Vomiting
- Stomach pain
- Nausea
- Indigestion
- Diarrhea
- Injection site reactions (pain, swelling, redness)
Similar Medicine Of Pirocol 20mg Injection
What If I Missed A Dose Of Pirocol 20mg Injection
- Don't skip any drug of the dose. If forgotten, take it once remembered.
- If the next dose time is near, skip the missed one.
- Avoid doubling to compensate. Follow this routine for safe and effective usage.
- For guidance on managing missed doses, consult your healthcare provider, ensuring proper adherence to the prescribed regimen.
Health And Lifestyle
Avoid overuse of alcohol. Maintain Balance diet and stay hydrated. If you are regularly exercising than incorporate light exercise to manage pain and Inflammation better.
Drug Interaction
- Anticoagulants (e.g., Warfarin)
- Antihypertensives (e.g., ACE inhibitors)
Drug Food Interaction
- Alcohol
- Grapefruit Juice
Disease Explanation
Pain- Pain signals the nervous system that something may be wrong, and can be sharp or dull, coming or going. It can be experienced in one area or all over. There are two types of pain: acute and chronic. Acute pain, sudden and often treated, can go away, while chronic pain can last for years and cause severe problems.
FAQ's on Pirocol 20mg Injection
Can I use Pirocol if I am a diabetic?
Pirocol in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pirocol so taking piroxicam can lead to increased risk of renal failure by many folds.
Can Pirocol be used with methocarbamol?
Yes. Methocarbamol can be used with Pirocol as no serious side effects are known. Inform your doctor before starting any of the medication.
Can I use Pirocol for a migraine?
Pirocol is not approved for the treatment of migraine. Research studies have shown that Pirocol is effective in significantly decreasing the pain associated with migraine without aura.
Are there any alternatives of Pirocol?
Yes. There are alternatives to Pirocol. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Can Pirocol lead to skin reactions?
Yes. Pirocol is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
What are the serious side effects of Pirocol?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
What is the difference between Pirocol and diclofenac?
Both Pirocol and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pirocol.
Can Pirocol be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pirocol or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pirocol.
Can Pirocol lead to difficulty in conception?
Yes. Pirocol can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Can Pirocol be used with warfarin?
No. Pirocol should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Is Pirocol a muscle relaxant?
No. Pirocol is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Can Pirocol be used along with dexamethasone?
No. Pirocol should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.
Can I use Pirocol if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Can you donate blood when on the medication with Pirocol?
Yes. You can donate blood when on Pirocol. Do inform your doctor before donating blood.
Can Pirocol be used with Lisinopril?
No. Pirocol should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirocol.
Is Pirocol a sulfa drug?
Pirocol is a sulphur containing compound. Pirocol can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Can I use Pirocol if I am pregnant?
No. Pirocol should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Can Pirocol be used with diuretics?
No. Pirocol should not be used with diuretics. Pirocol reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can Pirocol be used in the treatment of allergy?
No. Pirocol is not a drug to treat allergy. It is a pain killer.
Can Pirocol be used along with paracetamol?
Yes. Paracetamol can be used with Pirocol as no serious side effects are known. Inform your doctor before starting any of the medication.
Why is beta cyclodextrin added to Pirocol?
Yes. Pirocol can be combined with beta-cyclodextrin. Research has shown that combining Pirocol with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
What is the difference between Pirocol and naproxen?
Both Pirocol and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pirocol.
What are the contraindications for Pirocol?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
What is the difference between Pirocol and meloxicam?
Both Pirocol and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pirocol.
Can I use Pirocol if I have peptic ulcer disease?
No. Pirocol is contraindicated in cases of active peptic ulcer disease. Pirocol is known to cause gastric ulceration and bleeding.
Are Pirocol and aspirin same?
No. Pirocol and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can you get high by using Pirocol?
No. Pirocol is not known to cause high. It is a non-narcotic painkiller.
Can Pirocol be used with Tizanidine?
Yes, Pirocol can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Is Pirocol a NSAID?
Yes. Pirocol is a non-steroidal anti-inflammatory drug (NSAID).
Is Pirocol affective in gout management?
Yes. Pirocol can be given for the treatment of acute gout. Research studies have shown Pirocol to be highly effective in the treatment of acute gout.
Is Pirocol a blood thinner?
No. Pirocol is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
What increases the chances of getting a gastric ulcer when I am already taking Pirocol?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
What is the difference between Pirocol and tramadol?
Pirocol is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Can Pirocol be used with calcium channel blocker?
Yes. Pirocol can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Is Pirocol a narcotic?
No. Pirocol is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Can I use Pirocol if I have a deranged renal function?
No. Pirocol should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
What is the difference between Pirocol and ketoprofen?
Both Pirocol and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pirocol. Ketoprofen gel also showed excellent tolerability.
Can Pirocol be used in hypertension?
No. Pirocol is not a medication to control hypertension. It is important to note that Pirocol decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pirocol.
Can Pirocol be used with lithium?
No. Pirocol should not be used with lithium. Pirocol leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
How long does Pirocol work?
Pirocol is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Is Pirocol effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pirocol as the cause of back pain can be different for different person.
Can Pirocol be used to treat menstrual cramp?
Pirocol is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
What is the difference between Pirocol and nimesulide?
Both Pirocol and nimesulide are pain killers. However, Pirocol is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Can Pirocol be used along with Losartan?
No. Pirocol should not be combined with Losartan. It is important to note that Pirocol decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirocol.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pirocol?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Written By
Rakshita Garg
M.Pharma
Content Updated on
Saturday, 27 July, 2024Prescription Required
Pirocol 20mg Injection
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