Prescription Required

Velpanat 400mg/100mg Tablet 28s

by Natco Pharma Ltd

₹17500₹15750

10% off
Velpanat 400mg/100mg Tablet 28s

Introduction to Velpanat 400mg/100mg Tablet 28s

Velpanat Tablet is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection.Velpanat Tablet is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.
Velpanat Tablet should be taken in the prescribed dose and duration. It can be taken with or without food, but take it at the same time daily. It is advised not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver or kidney disease. It is harmful to consume alcohol along with this medicine, so it is advised to limit or avoid alcohol. The course of the medicine should be completed for better results.
 

Safety Advice for Velpanat 400mg/100mg Tablet 28s

  • High risk
  • Moderate risk
  • Safe
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Alcohol consumption can exacerbate liver damage. It is highly advisable to avoid alcohol while on Velpanat treatment, as it may reduce the effectiveness of the medication and worsen liver function.

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Velpanat Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby however, there are limited human studies.

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Velpanat Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

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Velpanat Tablet may cause side effects which could affect your ability to drive.<BR>Velpanat Tablet, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive.

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Velpanat Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Velpanat Tablet may be needed. Please consult your doctor.<BR>Limited information is available on the use of Velpanat Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

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Velpanat Tablet is safe to use in patients with liver disease. No dose adjustment of Velpanat Tablet is recommended.<BR>However, inform your doctor if you have any kidney disease as regular monitoring of liver function tests may be advised in some patients while taking this medicine.

How Velpanat 400mg/100mg Tablet 28s works

Velpanat 400mg/100mg Tablet combines Sofosbuvir and Velpatasvir, two powerful antivirals that target hepatitis C at different stages of its lifecycle. Sofosbuvir, a nucleotide analogue, inhibits the HCV polymerase enzyme, preventing viral replication and spread. Velpatasvir, a pan-genotypic NS5A inhibitor, disrupts viral replication and assembly, making it harder for the virus to multiply. Together, these medications work synergistically to eliminate the hepatitis C virus, improve liver health, and reduce the risk of complications associated with chronic infection.

How To Use Velpanat 400mg/100mg Tablet 28s

  • Dosage: Take one tablet of Velpanat 400mg/100mg daily with or without food.
  • Administration: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
  • Consistency: For the best results, take the tablet at the same time every day.

Special Precautions About Velpanat 400mg/100mg Tablet 28s

  • Kidney Function: Before using Velpanat, your doctor will assess your kidney function. People with moderate or severe renal impairment may need dose adjustments.
  • Drug Resistance: If you have previously received HCV treatment, tell your doctor to ensure that this treatment is appropriate for your condition.
  • Hepatitis B: If you are co-infected with hepatitis B, additional monitoring and treatment may be required.

Benefits Of Velpanat 400mg/100mg Tablet 28s

  • Cure Hepatitis C: Velpanat has been shown to cure hepatitis C in most patients, leading to improved liver health.
  • No Interferon Required: Unlike traditional hepatitis C treatments, Velpanat does not require interferon injections, making it a more convenient treatment option.
  • Pan-Genotypic: It is effective against all genotypes of hepatitis C, making it a versatile treatment option.

Side Effects Of Velpanat 400mg/100mg Tablet 28s

  • Headache
  • Tiredness

Similar Medicine Of Velpanat 400mg/100mg Tablet 28s

What If I Missed A Dose Of Velpanat 400mg/100mg Tablet 28s

  • Take the missed dose as soon as you remember.
  • If it’s almost time for your next dose, skip the missed dose.
  • Do not take two doses at once to compensate for the missed dose.

Health And Lifestyle

Maintain a balanced diet to support liver health during your treatment, avoiding alcohol and high-fat foods. Schedule regular checkups with your healthcare provider for liver function tests to monitor treatment progress. Stay hydrated by drinking plenty of water to help your body eliminate toxins effectively.

Drug Interaction

  • Rifampin: May reduce the effectiveness of Velpanat. Avoid using both drugs simultaneously.
  • Antacids: Antacids may interfere with the absorption of Velpanat, so space them out by at least 4 hours.
  • HIV Medications: Some HIV medications may interact with Velpanat, so inform your healthcare provider if you're on antiretroviral therapy.

Drug Food Interaction

  • Grapefruit: Avoid consuming grapefruit or grapefruit juice, as it can interfere with the absorption of Velpanat and affect its efficacy.
  • High-Fat Meals: High-fat meals may alter the absorption of Velpanat. It's best to take the tablet with a regular meal.

Disease Explanation

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Hepatitis C is a viral infection that affects the liver, often leading to chronic liver disease, cirrhosis, or liver cancer. The infection is caused by the hepatitis C virus (HCV), which is transmitted through blood-to-blood contact. Velpanat is a combination treatment that targets and eradicates HCV, helping to prevent the progression of liver damage.

Tips of Velpanat 400mg/100mg Tablet 28s

Monitor liver function: Regular monitoring of liver enzymes and function is essential during treatment.,Stay on schedule: For the best results, it’s important to adhere to your treatment schedule without skipping doses.,Avoid self-medication: Do not start or stop medications without consulting your doctor to prevent drug interactions or resistance.

FactBox of Velpanat 400mg/100mg Tablet 28s

  • Salt Composition: Sofosbuvir (400mg) + Velpatasvir (100mg)
  • Pack Size: 28 tablets
  • Usage: Treatment of chronic hepatitis C
  • Manufacturer: Natco Pharma

Storage of Velpanat 400mg/100mg Tablet 28s

Store Velpanat in a cool, dry place away from direct sunlight and out of reach of children. Do not use the medication past its expiration date.


 

Dosage of Velpanat 400mg/100mg Tablet 28s

The recommended dosage of Velpanat 400mg/100mg Tablet is one tablet daily. Follow your healthcare provider's instructions regarding the exact dosage and duration based on your condition.

Synopsis of Velpanat 400mg/100mg Tablet 28s

Velpanat 400mg/100mg Tablet is a combination treatment for hepatitis C that offers high efficacy and minimal side effects. By inhibiting viral replication through Sofosbuvir and Velpatasvir, it helps patients achieve a sustained virologic response (SVR), leading to a potential cure of hepatitis C.


 

FAQ's on Velpanat 400mg/100mg Tablet 28s

What is Velpanat used for?

Velpanat is used to treat chronic hepatitis C virus (HCV) infections in adults. It is effective against all six major HCV genotypes and helps reduce viral load in the body, potentially leading to a cure.

How does Velpanat work to treat hepatitis C?

Velpanat contains two antiviral agents: Sofosbuvir: Inhibits the HCV polymerase enzyme, preventing the virus from replicating. Velpatasvir: Blocks the NS5A protein, which is essential for the virus’s assembly and spread. Together, they work to eliminate the hepatitis C virus from the body.

Can I take Velpanat with other medications?

Velpanat may interact with certain medications, including antacids, proton pump inhibitors, rifampin, and some seizure medications. Always inform your doctor about any other medications or supplements you are taking before starting Velpanat.

Are there any side effects of Velpanat?

Common side effects of Velpanat include: Fatigue Headache Nausea Insomnia Diarrhea Serious side effects are rare but may include allergic reactions or worsening liver function in patients with advanced liver disease.

How long does it take for Velpanat to work?

Velpanat is usually prescribed for 12 weeks (sometimes longer for certain patients). A healthcare provider will monitor viral load levels to determine if the treatment is effective.

Can I drink alcohol while on Velpanat?

It is best to avoid alcohol while taking Velpanat, as alcohol can strain the liver and interfere with the effectiveness of the treatment.

Is Velpanat safe during pregnancy?

The safety of Velpanat during pregnancy has not been fully established. Pregnant women or those planning to conceive should consult their doctor before using this medication.

Can I take Velpanat if I have kidney problems?

What should I do if I miss a dose of Velpanat?

What should I do if I miss a dose of Velpanat?

Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not take two doses at once to compensate for a missed dose.

How should Velpanat be stored?

Store Velpanat at room temperature (15°C – 30°C) in a dry place, away from moisture, heat, and direct sunlight. Keep it out of reach of children and pets.

Can I take Velpanat with food?

Yes, Velpanat can be taken with or without food. However, taking it with food may help reduce nausea in some individuals.

What is the recommended dosage of Velpanat?

The usual dosage is one tablet (400mg Sofosbuvir + 100mg Velpatasvir) per day for 12 weeks. Always follow your doctor’s prescribed dosage.

Can Velpanat cure hepatitis C completely?

Yes, Velpanat has a high cure rate (over 95%) when taken correctly. A sustained virologic response (SVR) test after treatment confirms whether the virus has been eliminated from the body.

How does Sofosbuvir in Velpanat work?

Sofosbuvir is a nucleotide polymerase inhibitor that blocks the replication of the hepatitis C virus, preventing it from multiplying.

Is Velpanat a pan-genotypic drug?

Yes, Velpanat is pan-genotypic, meaning it is effective against all six major hepatitis C genotypes.

What should I avoid while taking Velpanat?

Grapefruit or grapefruit juice (may interfere with drug absorption). St. John’s Wort (a herbal supplement that can reduce Velpanat’s effectiveness). Certain antacids and acid reducers (consult your doctor before using them).

Is Velpanat available without a prescription?

No, Velpanat is a prescription-only medication and should only be used under a doctor’s supervision.

Can Velpanat cause liver problems?

Velpanat is designed to improve liver function by treating hepatitis C. However, in rare cases, it may cause liver complications in patients with advanced cirrhosis or other liver conditions.

How do I know if Velpanat is working for me?

Regular blood tests will measure viral load levels. A significant drop in the virus count indicates that the medication is working. After completing the course, a sustained virologic response (SVR) test is done to confirm a cure.

Can I take Velpanat if I have other health conditions?

Patients with liver disease, kidney disease, HIV, or other serious health conditions should consult their doctor before taking Velpanat to ensure its safety and effectiveness.

check.svg Written By

Harsh Thakur

Content Updated on

Tuesday, 11 March, 2025

Prescription Required

Velpanat 400mg/100mg Tablet 28s

by Natco Pharma Ltd

₹17500₹15750

10% off
Velpanat 400mg/100mg Tablet 28s

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