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Tasigna 150mg Capsule falls under the category of tyrosine kinase inhibitors that are employed in the management of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), a specific form of blood malignancy. Ph+ CML leads to unusual function in white blood cells.
The active ingredient is Nilotinib, which halts the activity of an aberrant protein (Bcr-Abl tyrosine kinase) engendered by the Philadelphia chromosome. This protein jump-starts the abnormal white blood cells (cancerous cells) to increase in number. By blocking this trigger, Nilotinib stops the proliferation and expansion of malignant cells, ultimately resulting in their elimination. This process is instrumental in controlling Ph+ CML and plays a vital role in the treatment of this leukemia variation.
Headache, nausea, abdominal discomfort, and skin rashes are commonly observed side effects of this medicine. If you suffer from severe diarrhea, it’s essential to consult your physician or stay adequately hydrated while undergoing treatment. This drug might lower the blood cell count (reduce red and white blood cells) in your body, thus, escalating the risk of infections. Regular blood examinations are necessary to monitor your blood cells along with heart, liver and blood uric acid levels along with glucose or lipid level in the system.
Prior to commencing the treatment, inform your healthcare provider if you have a history of heart ailments, liver, or kidney diseases or are consuming any medicine to address infections. A significant number of other drugs could impact, or be influenced by, this medicine so it's vital that your healthcare team is aware of all medications you're currently taking. This drug is not advised during pregnancy or lactation. The use of reliable birth control methods by both men and women while on treatment is crucial to prevent pregnancy.
If you miss a dose of drug, take it as soon as you remember on the same day. If it is already the next day, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure about what to do, consult your healthcare provider or pharmacist for advice.
Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) is a type of cancer that starts in the bone marrow and affects the blood cells. It is characterized by the presence of an abnormal chromosome called the Philadelphia chromosome.
Content Updated on
Thursday, 16 January, 2025Prescription Required
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