Prescription Required

Imfinzi 500mg Injection

by AstraZeneca

Salt CompositionDurvalumab (500mg)

₹189585

(vial of 1 Injection)

Stock : Out of Stock

Introduction to Imfinzi 500mg Injection

Imfinzi 500mg Injection is a prescription medication used in the treatment of certain types of cancer, particularly non-small cell lung cancer (NSCLC) and urothelial carcinoma (a form of bladder cancer). It belongs to a class of medications known as immune checkpoint inhibitors and works by enhancing the immune system's ability to target and destroy cancer cells. The active ingredient, Durvalumab, binds to the PD-L1 protein on tumor cells, blocking its interaction with PD-1 receptors, which is a mechanism that cancers use to evade immune detection.

By blocking this interaction, Imfinzi enables the immune system to recognize and attack cancer cells more effectively. Imfinzi has been proven to help in prolonging survival and improving the quality of life for patients suffering from these aggressive cancers.

Safety Advice for Imfinzi 500mg Injection

High risk
Moderate risk
Safe

Liver function should be carefully monitored during Imfinzi treatment, as there may be risks of liver-related side effects. Your doctor may conduct regular liver function tests before and during your treatment.

Patients with kidney problems should consult their doctor before using Imfinzi 500mg Injection. While the medication does not have direct adverse effects on kidney function, your doctor will monitor your kidney health during treatment.

It is generally recommended to limit or avoid alcohol consumption while undergoing treatment with Imfinzi. Alcohol can affect your immune system and overall health, possibly reducing the effectiveness of cancer treatment.

Some people may experience side effects such as dizziness or fatigue. If you experience these symptoms, you should avoid driving or operating machinery until you feel better.

Imfinzi is not recommended during pregnancy unless absolutely necessary. Animal studies have shown that Durvalumab may harm the developing fetus. If you are pregnant or planning to become pregnant, discuss with your healthcare provider whether Imfinzi is appropriate for you.

It is unknown whether Durvalumab passes into breast milk. Due to the potential for serious side effects, it is advised to avoid breastfeeding during treatment with Imfinzi. Always consult your doctor before breastfeeding.

How Imfinzi 500mg Injection works

Imfinzi 500mg Injection contains Durvalumab, a monoclonal antibody that works by inhibiting the interaction between the PD-L1 protein (present on tumor cells) and the PD-1 receptor (found on T-cells of the immune system). When the PD-L1 protein binds to PD-1, it suppresses the immune system’s ability to attack cancer cells. By blocking this interaction, Durvalumab activates T-cells and enhances the immune system's ability to identify and destroy cancer cells. This helps to shrink tumors and slow cancer progression.

How To Use Imfinzi 500mg Injection

Dosage and Administration: Imfinzi 500mg Injection is administered intravenously (IV) by a healthcare professional. The recommended dosage typically depends on your specific medical condition, and your doctor will determine the appropriate schedule for your treatment. Typically, it is given once every two weeks or as directed by your healthcare provider.
Preparation: The injection should be given in a clinical or hospital setting where healthcare professionals can monitor for potential side effects. It is important to follow all medical instructions and attend all follow-up appointments.
Monitor Treatment: Your healthcare provider will closely monitor your response to treatment, including any side effects. It’s essential to inform your doctor of any unusual symptoms you experience during your treatment.

Special Precautions About Imfinzi 500mg Injection

Autoimmune Conditions: Imfinzi may cause immune-related side effects, such as inflammation in various organs. If you have a history of autoimmune diseases (e.g., rheumatoid arthritis, lupus), discuss this with your doctor, as you may require close monitoring or dosage adjustments.
Infections: The treatment may lower your immune system’s ability to fight infections. Inform your healthcare provider immediately if you develop signs of an infection, such as fever, chills, or a sore throat.
Organ Function: Monitor liver, kidney, and lung function regularly during treatment. Be aware of symptoms such as jaundice (yellowing of the skin or eyes), severe fatigue, or shortness of breath, which could indicate serious side effects.

Benefits Of Imfinzi 500mg Injection

Effective Against Various Cancers: Imfinzi has demonstrated efficacy in treating non-small cell lung cancer (NSCLC), urothelial carcinoma, and other cancers, offering patients hope for improved survival rates.
Improved Immune Response: By stimulating the immune system to target cancer cells, Imfinzi offers a novel approach to cancer treatment with fewer direct side effects compared to traditional chemotherapy.
Prolonged Survival: Clinical studies have shown that Imfinzi can help prolong survival in patients with advanced cancers, improving their quality of life.

Side Effects Of Imfinzi 500mg Injection

Fatigue
Decreased appetite
Skin rash
Nausea
Diarrhea

What If I Missed A Dose Of Imfinzi 500mg Injection

If you miss a dose of Imfinzi, contact your healthcare provider immediately.
Reschedule your treatment as advised by your doctor.
Following the prescribed schedule is essential for optimal results.

Health And Lifestyle

Maintaining a healthy lifestyle can support overall well-being and enhance the effectiveness of cancer treatments. A balanced diet rich in fruits, vegetables, and lean proteins helps strengthen the immune system and improve recovery. Engaging in light exercise, as advised by your doctor, can boost energy levels, reduce fatigue, and improve mood. Additionally, seeking emotional and psychological support, such as counseling or support groups, can help manage the stress and anxiety associated with cancer treatment, promoting a positive outlook on the healing journey.

Drug Interaction

Corticosteroids: These drugs may reduce the effectiveness of Imfinzi. If you are on corticosteroids, your doctor will monitor your treatment closely.
Immunosuppressive Drugs: Combining Imfinzi with drugs that suppress the immune system could increase the risk of immune-related side effects.

Drug Food Interaction

There are no known specific food interactions with Imfinzi. However, maintaining a nutritious diet is important to help your body cope with the effects of cancer treatment.

Disease Explanation

Cancer occurs when abnormal cells grow uncontrollably and spread to other parts of the body. Imfinzi 500mg Injection is used to treat cancers where immune checkpoint inhibitors are effective, such as non-small cell lung cancer (NSCLC) and bladder cancer. NSCLC is the most common type of lung cancer, often requiring advanced treatments like immunotherapy. Urothelial carcinoma, a type of cancer affecting the bladder, can spread to other parts of the urinary tract. Imfinzi works by boosting the immune system’s ability to recognize and attack cancer cells, helping slow disease progression.

Tips of Imfinzi 500mg Injection

Attend Regular Checkups: It’s important to attend all scheduled appointments with your healthcare provider to monitor the progress of your treatment and manage side effects.,Stay Hydrated: Drinking enough water can help mitigate some side effects like fatigue and nausea.

FactBox of Imfinzi 500mg Injection

Active Ingredient: Durvalumab (500mg)
Form: Intravenous Injection
Indications: Non-Small Cell Lung Cancer (NSCLC), Urothelial Carcinoma, and more.
Storage: Store in the refrigerator (2°C – 8°C) and protect from light. Do not freeze.

Storage of Imfinzi 500mg Injection

Store Imfinzi 500mg Injection in a refrigerator. Keep it in its original carton to protect it from light. Do not freeze the injection. Ensure that it is kept out of reach of children and disposed of according to medical waste guidelines.

Dosage of Imfinzi 500mg Injection

General Dosage: The standard dosage is 500mg given once every two weeks by intravenous infusion. However, your doctor may adjust the dosage based on your condition and response to treatment.

Synopsis of Imfinzi 500mg Injection

Imfinzi 500mg Injection is an advanced cancer treatment designed to enhance the body’s immune system in its fight against certain types of cancer. With the active ingredient Durvalumab, it offers effective treatment for non-small cell lung cancer and urothelial carcinoma, improving survival rates and quality of life. Always follow your healthcare provider’s advice for optimal results.

FAQ's on Imfinzi 500mg Injection

What is Imfinzi used for?

Imfinzi (Durvalumab) is an immunotherapy used to treat certain types of cancer, including non-small cell lung cancer (NSCLC) and bladder cancer.

How does Imfinzi work?

Imfinzi is a PD-L1 inhibitor that helps the immune system recognize and attack cancer cells by blocking the PD-L1 protein, which tumors use to evade immune response.

Can I drink alcohol while using Imfinzi?

It is best to avoid alcohol while taking Imfinzi, as it may worsen side effects like fatigue and liver issues.

Is Imfinzi safe during pregnancy?

Imfinzi is not recommended during pregnancy as it may harm the unborn baby. Discuss birth control options with your doctor.

How often is Imfinzi administered?

Imfinzi is typically given as an intravenous (IV) infusion every 2 or 4 weeks, depending on the treatment plan.

What are the side effects of Imfinzi?

Common side effects include fatigue, nausea, cough, skin rash, loss of appetite, and immune-related reactions affecting the lungs, liver, or intestines.

How long can I take Imfinzi?

The duration of treatment depends on the type of cancer and individual response. It is usually given for up to 12 months or as long as it remains effective.

Can I take Imfinzi with other medications?

Imfinzi can interact with other drugs, especially immunosuppressants and corticosteroids. Inform your doctor about all medications you are taking.

Is there a generic version of Imfinzi?

No, Imfinzi (Durvalumab) is a brand-name drug, and currently, no generic versions are available.

What happens if I miss a dose of Imfinzi?

If you miss a dose, contact your doctor immediately to reschedule your infusion. Sticking to the prescribed schedule is important for treatment effectiveness.

Can Imfinzi be used for other cancers?

Yes, Imfinzi is approved for NSCLC and bladder cancer, and it is being studied for use in other cancers.

Does Imfinzi interact with food?

There are no known food interactions with Imfinzi, but maintaining a healthy diet is recommended to support overall well-being.

How is Imfinzi administered?

Imfinzi is given as an intravenous (IV) infusion by a healthcare professional in a hospital or clinic setting.

Are there any alternatives to Imfinzi?

Other immunotherapy drugs, such as Keytruda (Pembrolizumab) and Opdivo (Nivolumab), may be alternatives depending on the cancer type.

Is Imfinzi effective for advanced cancer?

Yes, Imfinzi has shown effectiveness in treating advanced or metastatic cancer, particularly in NSCLC and bladder cancer.

Can I drive after receiving Imfinzi?

Imfinzi may cause fatigue or dizziness, so avoid driving if you experience these side effects.

What should I do if I experience side effects from Imfinzi?

Report any side effects to your doctor immediately, especially severe symptoms like difficulty breathing, chest pain, or liver problems.

Can I use Imfinzi for lung cancer?

Yes, Imfinzi is approved for non-small cell lung cancer (NSCLC) and is used to prevent recurrence after chemotherapy and radiation.

How can I manage side effects from Imfinzi?

Stay hydrated, eat a balanced diet, get enough rest, and follow your doctor''s advice to manage side effects effectively.

Is Imfinzi a long-term treatment?

Imfinzi is usually prescribed for up to a year, but the duration may vary based on cancer progression and individual response to treatment.

Written By

Harsh Thakur

Content Updated on

Monday, 17 March, 2025

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Imfinzi 500mg Injection

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