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Prescription Required

Hervycta 150 Injection

by Dr Reddy s Laboratories Ltd
Trastuzumab (150mg)

₹20300

Hervycta 150 Injection

Introduction to Hervycta 150 Injection

Hervycta 150 Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, rash, insomnia, and infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must have to inform your doctor if you experience breathlessness, cough, shivering, swelling of legs and arm.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Safety Advice for Hervycta 150 Injection

  • High risk
  • Moderate risk
  • Safe
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Hervycta 150 Injection may cause excessive drowsiness with alcohol.

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Hervycta 150 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

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Hervycta 150 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

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It is not known whether Hervycta 150 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

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Hervycta 150 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Hervycta 150 Injection may not be needed in these patients. Please consult your doctor.

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There is limited information available on the use of Hervycta 150 Injection in patients with liver disease. Please consult your doctor.

How Hervycta 150 Injection works

Hervycta 150 Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

How To Use Hervycta 150 Injection

  • Your doctor or nurse will give you this medicine. Kindly do not self administer.

Side Effects Of Hervycta 150 Injection

  • Anemia (low number of red blood cells)
  • Chills
  • Common cold
  • Cough
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea
  • Fatigue
  • Fever
  • Headache
  • Heart failure
  • Infection
  • Insomnia (difficulty in sleeping)
  • Mucosal inflammation
  • Nausea
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Taste change
  • Upper respiratory tract infection
  • Weight loss

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FAQ's on Hervycta 150 Injection

How frequently heart investigations are required?

Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Hervycta. Those patients who already have heart-related problems will require investigations every 12 weeks.

Can Hervycta be given to HER2 negative cancer patients?

No, Hervycta cannot be given in patients with HER2 negative cancer cells. Hervycta belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Hervycta binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).

How long should Hervycta be taken?

Patients with early breast cancer should take Hervycta for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

What are the serious side effects of Hervycta?

There are various side effects related to Hervycta such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Hervycta. You should call your doctor immediately if you notice any such symptoms.

How is Hervycta given, intravenously or intramuscularly?

There are 2 different formulations available for administration of Hervycta, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Hervycta intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Hervycta intravenous treatment to Hervycta subcutaneous treatment (and vice versa) if considered appropriate for you.

How long after Hervycta therapy can I get pregnant?

Women of child-bearing age should use effective contraception during Hervycta therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Hervycta.

Is fasting required before administering Hervycta?

No, fasting is not required before administering Hervycta. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.

Why has my doctor advised for investigations of heart?

Hervycta when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.

Prescription Required

Hervycta 150 Injection

by Dr Reddy s Laboratories Ltd
Trastuzumab (150mg)

₹20300

Hervycta 150 Injection

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