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Introduction to Combiflam 400mg/325mg Tablet 20s
Combiflam 400/325 mg Tablet is a widely used pain reliever and anti-inflammatory medicine that provides effective relief from pain, inflammation, and fever. It contains a combination of Ibuprofen (400mg) and Paracetamol (325mg), making it useful for headaches, muscle pain, joint pain, fever, and menstrual cramps.
Safety Advice for Combiflam 400mg/325mg Tablet 20s
- High risk
- Moderate risk
- Safe
There is no sufficient information available regarding Alcohol consumption.
Exercise caution when using it in individuals with kidney disease.
Combiflam Tablet should be used cautiously in patients with pre-existing liver disease.
There is no sufficient information available regarding the use of it during pregnancy.
There is no sufficient information available regarding the use of it during breastfeeding.
There is no sufficient information available regarding driving.
How Combiflam 400mg/325mg Tablet 20s works
Ibuprofen blocks enzymes (COX-1 & COX-2) responsible for pain and inflammation, providing relief from swelling and discomfort. Paracetamol works by reducing the production of prostaglandins in the brain, lowering fever and providing additional pain relief. Together, they provide faster and more effective relief from mild to moderate pain and fever.
How To Use Combiflam 400mg/325mg Tablet 20s
- Dosage: Take one tablet every 6-8 hours, or as prescribed by your doctor.
- Administration: Swallow Combiflam tablet whole with water, preferably after meals to avoid stomach upset.
- Duration: Do not exceed 3 days for fever and 5 days for pain without consulting a doctor.
Special Precautions About Combiflam 400mg/325mg Tablet 20s
- Stomach Problems: Avoid prolonged use if you have a history of acidity, ulcers, or gastritis, as NSAIDs may cause stomach irritation.
- Heart Patients: People with high blood pressure or heart disease should use Combiflam cautiously, as Ibuprofen may increase blood pressure.
Benefits Of Combiflam 400mg/325mg Tablet 20s
- Relieves pain caused by headaches, toothaches, menstrual cramps, and muscle aches.
- Reduces inflammation in conditions like arthritis, sprains, and joint pain.
- Lowers fever effectively in viral infections, flu, and colds.
- Acts quickly for fast pain relief compared to single-ingredient painkillers.
Side Effects Of Combiflam 400mg/325mg Tablet 20s
- Common Side Effects: Nausea, stomach pain, heartburn, dizziness, drowsiness.
- Serious Side Effects: Severe stomach pain, vomiting blood, black stools, allergic reactions (rash, swelling, breathing difficulty).
Similar Medicine Of Combiflam 400mg/325mg Tablet 20s
What If I Missed A Dose Of Combiflam 400mg/325mg Tablet 20s
- Use medicine as you remember to take. If the next dose is upcoming, skip the missed Dose.
- Do not double up for the compensation of missed Doses.
- If you miss a dose frequently then consult your Doctor.
Health And Lifestyle
Drink plenty of water to stay hydrated and help your body recover. Avoid spicy and oily foods if you experience stomach irritation. Rest properly and avoid strenuous activities while recovering. Do not take on an empty stomach to prevent acidity or stomach pain. Use alternative pain relief methods (e.g., ice packs, warm compresses) along with medication for better results.
Drug Interaction
- Blood Thinners (e.g., Warfarin, Aspirin) – May increase the risk of bleeding.
- Other NSAIDs (e.g., Diclofenac, Naproxen) – Avoid combining to prevent stomach ulcers and kidney damage.
- Steroids (e.g., Prednisolone) – Can increase stomach irritation and risk of bleeding.
- Blood Pressure Medicines (e.g., ACE inhibitors, Beta-blockers) – May reduce their effectiveness.
Drug Food Interaction
- No drug food interaction
Disease Explanation
Headache – A common condition caused by stress, tension, or dehydration, leading to pain in the head or neck region. Fever – A temporary rise in body temperature due to infection, which helps the immune system fight illness. Arthritis – A chronic inflammatory condition affecting joints, causing pain, swelling, and stiffness. Muscle & Joint Pain – Caused by physical strain, injury, or inflammation of soft tissues.
Tips of Combiflam 400mg/325mg Tablet 20s
Take after meals to reduce the risk of stomach irritation.,Do not use continuously for more than 5 days without consulting a doctor.,Keep out of reach of children, as accidental overdose can be harmful.
FactBox of Combiflam 400mg/325mg Tablet 20s
- Manufacturer: Sanofi India Ltd
- Composition: Ibuprofen (400mg) + Paracetamol (325mg)
- Class: Analgesic (Pain Reliever) & Antipyretic (Fever Reducer)
- Uses: Relief from pain, inflammation, and fever
- Prescription: Available without a prescription (OTC)
- Storage: Store below 30°C in a dry place, away from direct sunlight
Storage of Combiflam 400mg/325mg Tablet 20s
- Store in a cool, dry place below 30°C.
- Keep in original packaging to protect from moisture.
- Keep out of reach of children.
Dosage of Combiflam 400mg/325mg Tablet 20s
Adults & Children (above 12 years): 1 tablet every 6-8 hours, as needed.,Do not exceed 3 tablets per day unless advised by a doctor.
Synopsis of Combiflam 400mg/325mg Tablet 20s
Combiflam 400/325 mg Tablet is a trusted pain reliever and fever reducer that combines Ibuprofen and Paracetamol for faster and more effective relief from headaches, fever, joint pain, and inflammation. It is commonly used for short-term pain management, but long-term use should be avoided due to potential side effects.
FAQ's on Combiflam 400mg/325mg Tablet 20s
Can the use of Combiflam Tablet cause nausea and vomiting?
Yes, the use of Combiflam Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.
Is Combiflam Tablet helpful in relieving stomach pain?
No, Combiflam Tablet should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Can the use of Combiflam Tablet cause dizziness?
Yes, the use of Combiflam Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for sometime and resume once you feel better.
Are there any specific contraindications associated with the use of Combiflam Tablet?
The use of Combiflam Tablet is considered to be harmful for patients with known allergy to any of the components of this medicine. It should be avoided in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active or recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.
Is it safe to take a higher than the recommended dose of Combiflam Tablet ?
No, taking a higher than the recommended dose of Combiflam Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion and diarrhea. In fact, using this medicine for a long-term can also damage your kidneys on long-term use. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.
Can the use of Combiflam Tablet cause damage to kidneys?
Yes, the long-term use of Combiflam Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lowers the levels of prostaglandins in the body, leading to kidney damage because of long-term use. Therefore, the use of painkillers is not recommended in patients with underlying kidney disease.
Can I stop taking Combiflam Tablet when my pain is relieved?
Combiflam Tablet should be continued as advised by your doctor, if you are using the medicine for a condition associated with long-term pain. It can be discontinued if you are using it for short-term pain relief.
Is it safe to use Combiflam Tablet?
Combiflam Tablet is safe for most patients. However, in some patients, it may cause some unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor if you experience any persistent problem due to this medication.
What is Combiflam used for?
It is used to relieve pain, inflammation, and fever in conditions like headaches, muscle pain, and arthritis.
How quickly does Combiflam work?
It starts working within 30-60 minutes, providing relief for 4-6 hours.
Is Combiflam safe for daily use?
No, it should not be used for more than 5 consecutive days without medical supervision.
Can I take Combiflam for menstrual cramps?
Yes, it effectively relieves menstrual pain and cramps.
Does Combiflam cause drowsiness?
No, it does not usually cause drowsiness, making it suitable for daytime use.
What should I do if I overdose on Combiflam?
Seek immediate medical help, as overdose may cause liver and kidney damage.
Can children take Combiflam?
It is not recommended for children under 12 years.
Does Combiflam help with back pain?
Yes, it can relieve back pain caused by inflammation or muscle strain.
Can I take Combiflam if I have high blood pressure?
Use with caution, as Ibuprofen may increase blood pressure.
Can I take Combiflam and Paracetamol together?
No, as Combiflam already contains Paracetamol, additional Paracetamol may cause overdose.
Is Combiflam safe for kidney patients?
Not recommended for people with kidney disease unless prescribed.
Written By
Pranav ayush
MBA in Pharmaceutical
Content Updated on
Tuesday, 25 March, 2025Prescription Required
Combiflam 400mg/325mg Tablet 20s
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