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Biceltis 440mg Injection
Biceltis 440mg Injection
Biceltis 440mg Injection
Biceltis 440mg Injection
Biceltis 440mg Injection
Biceltis 440mg Injection

Prescription Required

Biceltis 440mg Injection

by Cipla Ltd
Trastuzumab (440mg)

₹75000

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Introduction to Biceltis 440mg Injection

Biceltis 440mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, rash, insomnia, and infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must have to inform your doctor if you experience breathlessness, cough, shivering, swelling of legs and arm.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How Biceltis 440mg Injection works

Biceltis 440mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

How To Use Biceltis 440mg Injection

  • Your doctor or nurse will give you this medicine. Kindly do not self administer.

Side Effects Of Biceltis 440mg Injection

  • Anemia (low number of red blood cells)
  • Chills
  • Common cold
  • Cough
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea
  • Fatigue
  • Fever
  • Headache
  • Heart failure
  • Infection
  • Insomnia (difficulty in sleeping)
  • Mucosal inflammation
  • Nausea
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Taste change
  • Upper respiratory tract infection
  • Weight loss

Safety Advice for Biceltis 440mg Injection

  • High risk
  • Moderate risk
  • Safe
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Biceltis 440mg Injection may cause excessive drowsiness with alcohol.

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Biceltis 440mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

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Biceltis 440mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

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It is not known whether Biceltis 440mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

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Biceltis 440mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Biceltis 440mg Injection may not be needed in these patients. Please consult your doctor.

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There is limited information available on the use of Biceltis 440mg Injection in patients with liver disease. Please consult your doctor.

FAQ's on Biceltis 440mg Injection

How long should Biceltis be taken?

Patients with early breast cancer should take Biceltis for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

Is fasting required before administering Biceltis?

No, fasting is not required before administering Biceltis. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.

How long after Biceltis therapy can I get pregnant?

Women of child-bearing age should use effective contraception during Biceltis therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Biceltis.

How frequently heart investigations are required?

Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Biceltis. Those patients who already have heart-related problems will require investigations every 12 weeks.

What are the serious side effects of Biceltis?

There are various side effects related to Biceltis such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Biceltis. You should call your doctor immediately if you notice any such symptoms.

Why has my doctor advised for investigations of heart?

Biceltis when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.

How is Biceltis given, intravenously or intramuscularly?

There are 2 different formulations available for administration of Biceltis, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Biceltis intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Biceltis intravenous treatment to Biceltis subcutaneous treatment (and vice versa) if considered appropriate for you.

Can Biceltis be given to HER2 negative cancer patients?

No, Biceltis cannot be given in patients with HER2 negative cancer cells. Biceltis belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Biceltis binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).

check.svg Written By

KHUSHII HOTWANI

Content Updated on

Tuesday, 21 May, 2024
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